MBL or monoclonal B cell lymphocytosis is a condition where B-cells identical to those in CLL are found in low numbers in the blood stream. Although a small percentage of those with MBL progress to CLL, but the vast majority live a normal life.
CLL has always been thought to be rare in Asia, but recent research from China suggests it may be more common that we realized.
A bone marrow biopsy is not recommended as a routine part of the diagnosis or early management of CLL unless there are specific indications for the procedure.
Originally published in The CLL Tribune Q1 2017.