September 13, 2022

September 13, 2022

Stephen Feldman – Here Comes the Sun Cover

Stephen Feldman, a fellow chronic lymphocytic leukemia (CLL) thriver since his diagnosis in 2014, has been playing the guitar since he was a kid. For him, singing and playing music have always provided a soothing and healing experience. Although his consistency with playing has waxed and waned over the

September 13, 2022

Dr. Shmuel Shoham on Convalescent Plasma for COVID-19 in Immunocompromised Patients

In this interview, Dr. Brian Koffman spoke with Dr. Shmuel Shoham, a Professor of Clinical Medicine at Johns Hopkins University. Dr. Shoham specializes in the infectious disease care of immunocompromised patients, including those with leukemias and lymphomas. They discussed the use of convalescent plasma to treat COVID-19.

September 13, 2022

ASH 2021: Dr. Jake Soumerai on Measurable Residual Disease-Guided Treatment of Chronic Lymphocytic Leukemia (CLL) with Venetoclax and Obinutuzumab plus Zanubrutinib

At the American Society of Hematology (ASH) 2021, our own Dr. Brian Koffman interviewed Dr. Jake Soumerai, a clinical investigator at Massachusetts General Hospital and an Assistant Professor at Harvard Medical School. They discussed MRD as a biomarker to direct treatment duration in a phase 2 clinical trial of

September 13, 2022

ASH 2021: Dr. Anthony Mato on Updated Results from the BRUIN Study of Non-Covalent BTK Inhibitor Pirtobrutinib

We discuss updated results from the BRUIN study, a phase 1/2 clinical trial of pirtobrutinib in patients with advanced B-cell malignancies, including CLL, who have received >2 prior therapies.

September 13, 2022

ASH 2021: Safety and Efficacy of Third Generation CD20 Targeted CAR-T (MB-106) for Treatment of Relapsed/Refractory B-NHL and CLL

Dr. Mazyar Shadman and colleagues presented this research at the American Society for Hematology annual meeting, which was held in December 2021 (ASH 2021).

September 13, 2022

ASH 2021: Phase II Study of Acalabrutinib and High-Frequency Low-Dose Subcutaneous Rituximab in Patients with Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Acalabrutinib plus high-frequency, low-dose subcutaneous rituximab is tolerable and effective. In addition, because it can be administered at home, it is more convenient and can decrease patient infection risk during pandemics. However, while it does control disease, it does not lead to undetectable measurable residual disease (uMRD).

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September 13, 2022

Stephen Feldman – Here Comes the Sun Cover

Dr. Shmuel Shoham on Convalescent Plasma for COVID-19 in Immunocompromised Patients

ASH 2021: Dr. Jake Soumerai on Measurable Residual Disease-Guided Treatment of Chronic Lymphocytic Leukemia (CLL) with Venetoclax and Obinutuzumab plus Zanubrutinib

ASH 2021: Dr. Anthony Mato on Updated Results from the BRUIN Study of Non-Covalent BTK Inhibitor Pirtobrutinib

ASH 2021: Safety and Efficacy of Third Generation CD20 Targeted CAR-T (MB-106) for Treatment of Relapsed/Refractory B-NHL and CLL

ASH 2021: Phase II Study of Acalabrutinib and High-Frequency Low-Dose Subcutaneous Rituximab in Patients with Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

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