CAR-T Special Edition: Volume 6 Issue 4

Welcome to the FOURTH 2020 Issue of The CLL Society Tribune:
CAR-T Special Edition

Yogi Berra is reported to have said, “It’s tough to make predictions, especially about the future.” How many of us saw COVID-19 coming? And then saw it staying around for nine months and counting, like some unwelcome house guest who never leaves? I will make no predictions concerning 2021 in general. But I am grateful to still be here with my loved ones, even if here means being socially isolated. My predictions are that in 2021 CAR-T therapy will be increasingly used for CLL and other blood cancers, will become even safer and more effective, and in the not-too-distant future will be considered a smart treatment option. In our final CLL Society Tribune for 2020, we have experts and patients sharing their CAR-T journeys. You will also read about those who are not only trying to catch a glimpse of the future, but also inventing new cellular therapies and combining them with other treatments to improve outcomes. Not just in the CLL space, but for other leukemias and lymphomas as well. There are reasons to be optimistic, as there is a whole lot of light at the end of this very long tunnel. Hold on! The future is bright. My own story with CAR-T serves as living proof of how well this therapy can work. Happy Holidays and may this season of miracles bring the miracle of peace and health to us all. Stay safe. Stay strong. We are all in this together.

Brian Koffman, MDCM (retired) co-founder, EVP and CMO CLL Society and CLL and CAR-T patient

Living Well With CLL

My Wild Cancer Adventure with Follicular NHL

By Laurie Adami – Patient

Read Laurie’s amazing story how CAR-T was a miraculous game changer!  Read more

Managing My CLL – Staying One Step Ahead

By Robert Levis – Patient

Read about Robert’s multi-step plan to always remain one step ahead and how CAR-T remains a viable option.  Read more

My Boston Marathon

By Michelle Palmer– Patient

Michelle tells her touching story on her long recovery after CAR-T therapy and how she won her own personal marathon.   Read more

Dr. Larry’s CAR-T Journey

By Larry Saltzman – Patient

Larry charts his CLL course for us as he describes how CAR-T and other therapies has helped him along his journey to become “clean and clear.”  Read more

CAR-T Resources

CAR-T Resource Page

CLL Society’s curated list of resources from other organizations. Read more

Ask & Tell

CAR-T Therapy Survey

Please take a moment to complete our brief, reader survey covering CAR-T Therapy. Read more.

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Learn more about CAR-T and other cellular therapies by visiting our webpage here.

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Did You Know?

CAR-T Facts

By Brian Koffman, MDCM (retired), MSEd

Dr. Koffman describes CAR-T and its use.  Read more

The Basics

CAR-T: Targets and Limitations

By Professor Constantine Tam

Dr. Tam breaks down areas of improvement for this very exciting and promising new technology. Read more

Beyond The Basics

Cellular Immunotherapy in The Management of Cancer

By Utkarsh Acharya, DO, FACP

Dr. Acharya dives deep into the explanation of CAR-T therapy, the current challenges, and what the future holds. Read more

Conference Coverage

ASH 2019: Dr. David Maloney on CAR-T therapy in CLL

By Brian Koffman, MDCM (retired), MSEd

At ASH 2019 in Orlando, Dr. Brian Koffman interviewed Dr. David Maloney about the future of CAR-T as it begins to move up in the treatment pathway. Watch The Interview

iwCLL 2019: Dr. Maloney on “Off the Shelf” CAR-T cells for CLL

By Brian Koffman, MDCM (retired), MSEd

At iwCLL 2019 in Edinburgh, Scotland, Dr. Brian Koffman catches up with Dr. David Maloney about the advantages and concerns of allogeneic CAR-T. Watch The Interview

Ask The Doctor: CAR-T Edition

By Brian Koffman, MDCM (retired), MSEd

Dr. Brian Koffman, Chief Medical Officer of the CLL Society, answers readers’ questions submitted to the CLL Society. Read more

Ask The Experts

Questions submitted by readers and answered by our CLL Society experts.

Ask The Doctor

By Richard Furman, MD

Dr. Richard Furman of Weill-Cornell Medical College answers readers’ questions submitted to the CLL Society. Read more

Ask The Pharmacist

By Thomas E Henry III, MBA, RPh, CPh

Thomas E Henry III, MBA, RPh, CPh from Burlington Consulting Associates answers readers’ pharmacy questions submitted to the CLL Society. Read more

Ask The Lab Scientist

By Susan J. Leclair, PhD, CLS (NCA)

Susan J. Leclair from University of Massachusetts Dartmouth answers readers’ lab scientist questions submitted to the CLL Society. Read more

The CLL Society Tribune is made possible in part by grant support from AbbVie, Astra Zeneca, Bristol Meyers Squibb, and Genentech.


The CLL Society does not provide medical advice or endorsements. Unless explicitly stated otherwise, all content in the CLL Tribune is the opinion or information of its author, not the CLL Society. This newsletter is for reference and educational purposes only and is not a substitute for medical advice. We do not guarantee the accuracy of any of the materials. Always contact your own doctor or other professional healthcare provider if you have any questions concerning your or your family’s health. Everyone’s circumstances are different.