ASCO 2023: Dr. Jennifer Woyach on Combination Ibrutinib, Venetoclax, and Obinutuzumab for Previously Untreated CLL
In the setting of the COVID-19 pandemic, progression-free survival with first-line ibrutinib + venetoclax + obinutuzumab treatment was not superior to ibrutinib + obinutuzumab for older patients with previously untreated CLL. Follow-up remains ongoing, and many patients in the ibrutinib + venetoclax + obinutuzumab arm achieved undetectable measurable residual disease.