Basic Biology Archives

July 14, 2023

ASH 2022: Effects of Acalabrutinib on T Cells in CLL

Bruton tyrosine kinase (BTK) degraders are a new therapeutic area that might be able to overcome mutations that cause resistance to BTK inhibitors.

November 24, 2021

Introduction to Immunity Part 4: Testing

As the immune system is complex, so is testing. The best testing for antigens is to isolate a protein large enough to be antigenic and specific enough so that it is only found in that one situation. You can choose a test for the presence of active inflammation

November 24, 2021

Introduction to Immunity Part 3

This article will repeat some of the earlier material, but you can still go back and reread them from past CLL Society Tribune editions, Introduction of Immunity Part 1 and Part 2. Let us put together all the factoids from the first two articles and see if we can

September 14, 2021

Introduction to Immunity Part 2

In this article we will review the specific defense system or the immune response. For those of you who like history, this system was first clarified in the 1960s, so our knowledge of it and its functions has grown by leaps and bounds.

June 11, 2021

Introduction to Immunity

This is a general introduction to one of the ways that your immune system tries to protect you. I have combined and simplified a fair number of steps in order to give the reader a general sense of the function.

May 26, 2021

ASH 2020: Dr. Alexey Danilov on the Chronic Lymphocytic Leukemia (CLL) Comorbidity Index for Predicting Survival and Tolerance of Ibrutinib

ASH 2020: Dr. Alexey Danilov on the chronic lymphocytic leukemia (CLL) comorbidity index for predicting survival and tolerance of ibrutinib

May 19, 2021

iwCLL 2019: Dr. Carlo Croce on the Role of MicroRNA in Chronic Lymphocytic Leukemia (CLL)

iwCLL 2019: Dr. Danilov Discusses the Role of B-cells and T-cells in CLL (Chronic Lymphocytic Leukemia)

May 6, 2021

ASH 2020: Dr. Adrian Wiestner on Early Detection of BTK Mutations Preceding Ibrutinib Relapse in Chronic Lymphocytic Leukemia (CLL)

In this ASH 2020 interview, Dr. Adrian Wiestner discusses the usefulness of early detection of BTK mutations.

May 6, 2021

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Basic Biology

ASH 2022: Effects of Acalabrutinib on T Cells in CLL

Introduction to Immunity Part 4: Testing

Introduction to Immunity Part 3

Introduction to Immunity Part 2

Introduction to Immunity

ASH 2020: Dr. Alexey Danilov on the Chronic Lymphocytic Leukemia (CLL) Comorbidity Index for Predicting Survival and Tolerance of Ibrutinib

iwCLL 2019: Dr. Carlo Croce on the Role of MicroRNA in Chronic Lymphocytic Leukemia (CLL)

ASH 2020: Dr. Adrian Wiestner on Early Detection of BTK Mutations Preceding Ibrutinib Relapse in Chronic Lymphocytic Leukemia (CLL)

iwCLL 2019: Dr. Danilov Discusses the Role of B-cells and T-cells in CLL (Chronic Lymphocytic Leukemia)

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