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The World’s Leading Authority for Chronic Lymphocytic Leukemia Patients

Targeted Therapies

Most new “small molecules” can be taken by mouth. Many work by blocking pathways that the cancer cells have pirated and become addicted to such as signaling pathways. Examples include ibrutinib, acalabrutinib, duvelisib and others. Others, such as venetoclax, remove blockades that the cancer has created which prevent natural cell death. These therapies target the cancer and spare most healthy cells.