Half of patients with Richter transformation responded to treatment with epcoritamab, and outcomes were even better when it was used as a first-line therapy.
In the first head-to-head comparison, patients with CLL who were treated with either pirtobrutinib or ibrutinib responded equally well to both treatments.
In a phase 1 trial, BTK degrader bexobrutideg produced very good response rates in heavily pretreated patients with CLL / SLL and was generally well-tolerated.
Because patients with CLL / SLL are living longer, they are facing other emerging health challenges that are reviewed in this article.
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