Basic Biology of CLL/SLL
Welcome to “The Short Course on Basic Biology of CLL!”
Action Items for Basic Biology
Learn about the normal structure and function of the lymphocytes that become cancerous in CLL/SLL.
Learn more about where we find them beyond the blood stream, namely in the bone marrow, the lymph nodes, and the spleen.
Understand what is meant by chronic versus acute leukemias and when we say that cancer is clonal.
Read the articles we’ve curated for you.
Click on the article links below.
- What is CLL (Chronic Lymphocytic Leukemia) and What is SLL (Small Lymphocytic Lymphoma)?
- What is Leukemia?
- What is Lymphoma?
- What’s in a Name… or Two Names?
- What is the Difference Between a Chronic and Acute Leukemia?
- Where Did it Come From?
- What are Lymphocytes?
- What About Clones and Subclones?
- Introduction to Immunity
- Introduction to Immunity Part 2
- Introduction to Immunity Part 3
- Introduction to Immunity Part 4
Learn about the normal structure and function of the lymphocytes that become cancerous in CLL/SLL.
Learn more about where we find them beyond the blood stream, namely in the bone marrow, the lymph nodes, and the spleen.
Read the articles we’ve curated for you.
Click on the article links below.
ADDITIONAL READING
In this ASH 2020 interview, Dr. Adrian Wiestner discusses the usefulness of early detection of BTK mutations.
iwCLL 2019: Dr. Danilov Discusses the Role of B-cells and T-cells in CLL (Chronic Lymphocytic Leukemia)
All our MRD educational efforts are directed at the non-medical reader, but they also endeavor to be a true reflection of what’s happening in professional research and in the cutting edge CLL clinic.
During iwCLL 2019, Dr. Constantine Tam gave us a look at how the genetics of CLL cells can change over time (clonal evolution) in response to treatment and escape control of that treatment (resistance).
ASH 2019 – Does an inherited defect in the germline ATM tumor suppressor gene contribute to the development of CLL? Dr. Jennifer Brown found that one in four CLL patients studied had a variance (mutation) in their ATM gene.
ASH 2019: Dr. Adrian Wiestner on clonal evolution in chronic lymphocytic leukemia (CLL)
RECENT NEWS
When appropriate, the CLL Society will be posting updates and background information on the present Coronavirus pandemic focusing on reliable primary sources of information and avoiding most of the news that is not directly from reliable medical experts or government and world health agencies.
