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What a difference a few hours can make: A dose of dexamethasone and a dose of tocilizumab put the brakes on a few CAR-Ts and calmed down the inflammation. BK is getting up and about… hoping to be discharged on Wednesday.
This degree and severity of joint inflammation have never been described before in CAR-T therapy. There is probably an important research benefit here that Brian, even while sick, is pushing to get published. Patty