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CLL Society Webinar On Demand: Revisiting PI3K Inhibitors for the Treatment of CLL: Are They Living Up to Their Promise?

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Revisiting PI3K Inhibitors for the Treatment of CLL:
Are They Living Up to Their Promise?

Recorded August 26, 2021


Patty Koffman
Co-Founder and Communications Director
CLL Society


Brian Koffman, MDCM (retired), DCFP, FCFP, DABFP, MSEd
Executive Vice President and Chief Medical Officer
CLL Society


Dr. Ian Flinn, MD, PhDDr. Ian Flinn, MD, PhD is the Director of Lymphoma Research at the Sarah Cannon Research Institute.  In this role, he oversees lymphoma research throughout Sarah Cannon and its affiliates. Dr. Flinn also serves as the director for the Sarah Cannon Center for Blood Cancer at Tennessee Oncology and TriStar Centennial Medical Center. Dr. Flinn’s research focuses on the development of new therapies for patients with lymphoma and chronic lymphocytic leukemia.  This research includes first in human to phase 3 trials with novel approaches such as immune effector cell therapies, inhibitors of the B cell receptor pathway, and BCL-2 inhibitors amongst others.  His research has been widely published in journals such as the New England Journal of Medicine, Lancet, Journal of Clinical Oncology and Blood.


Blocking the B-cell receptor (BCR) with ibrutinib and other BTKi drugs has revolutionized care in CLL. PI3K inhibitors also block that same receptor and are remarkably effective in treating CLL. Join Dr. Ian Flinn who will explain how these treatments work, the common side effects, and what role they might play in the future.

This program was made possible by grant support from Adaptive Biotechnologies and Bristol Myers Squibb