Question:
In a CLL Society article you mentioned, “A fourth jab is not recommended.” Can you tell me why? I also wanted to know how the booster ingredients are different from doses 1 and 2. Lastly, why is it recommended that if you got the Pfizer vaccine that you should get the Pfizer booster? NIH team has suggested Moderna.
Answer: Responding to question one, that is correct. There are no data to recommend a fourth jab at this time. The term “booster” implies the need to boost the immune response at specific intervals, for example, every 8-12 months. Our immune system has memory, and antibodies that tend to last far beyond 8-12 months, and most antibodies last for many years. Therefore, the term “booster” is a bit misleading, since frequent doses, such as annually, are unlikely to be necessary. It is more likely this third dose represents a 3-dose series of vaccination, which will hopefully provide long-lasting immune protection. This is similar to what is already done with certain childhood vaccinations, such as hepatitis B.
Responding to question two, the ingredients of the booster are exactly the same as the other two.
In regards to question three, we are supporting the CDC guidance at this time which recommends getting the same vaccine that you received before unless that vaccine brand is not available to you.
