Richter's Transformation Archives

July 8, 2021

EHA 2021: Dr. Anthony Mato on pirtobrutinib (LOXO-305) for Richter’s transformation in chronic lymphocytic leukemia (CLL)

At the annual meeting of the European Hematology Association (EHA) 2021, our own Dr. Brian Koffman interviewed Dr. Anthony Mato, Director of the CLL Program at Memorial Sloan Kettering Cancer Center. They discussed preliminary results from a clinical trial of pirtobrutinib (formerly LOXO-305) in a subset of patients with

April 15, 2021

ASH 2020: Dr. Arnon Nagler on Safety and Efficacy of CD19-CAR T Cells in Richter’s Transformation After Targeted Therapy for Chronic Lymphocytic Leukemia (CLL)

July 24, 2020

ASCO 2020 Top 12” #3: A multicenter phase II study of venetoclax plus dose-adjusted R-EPOCH (VR-EPOCH) for Richter’s syndrome

A multi-center phase II study of venetoclax plus dose-adjusted R-EPOCH (VR-EPOCH) for Richter’s syndrome

March 9, 2020

ASH 2019: Dr. Mato Discusses a Novel Triple Therapy Clinical Trial for CLL/SLL, Richter’s Transformation and other Lymphomas

In this interview, Dr. Mato discusses a Phase Ia/Ib Study Exploring the Synthetic Lethality of the Orally Administered Novel Bruton’s Tyrosine Kinase Inhibitor; DTRMWXHS-12 (DTRM-12), in combination with Everolimus (Afinitor®) and Pomalidomide (Pomalyst®) in Patients with Relapsed/Refractory CLL, DLBCL or Other B-Cell Lymphomas.

December 7, 2019

ASCO 2019: CLL Society Dr. Koffman’s Pick #7 “Stem Cell Transplant in Richter Transformation inn Chronic Lymphocytic Leukemia (CLL)”

Dr. Brian Koffman, the Executive Vice President (EVP) and Chief Medical Officer (CMO) of the CLL Society, counts down his top ten CLL related abstract from ASCO or the American Society of Clinical Oncology Annual Meeting held May 31 – June 4, 2019, Chicago, IL. #7 Outcomes of stem

November 4, 2019

EHA 2019: Dr. Matthew Davids On Richter’s Transformation in CLL (chronic lymphocytic leukemia)

Great progress has been made in treating chronic lymphocytic leukemia, but sadly the outcomes for Richter’s Transformation (RT)) or Richter’s Syndrome (RS) remain dismal. For more basic information on RT aka RS see: https://cllsociety.org/2017/04/richter-transformation/. For more in general including clinical trials, see: https://cllsociety.org/?s=Richter Briefly, RT is when the usually

June 22, 2019

ASH 2018: Dr. Wang on Richter’s Transformation in CLL (chronic lymphocytic leukemia)

Richter’s Transformation (RT) or Richter’s Syndrome (RS) remains a major unmet need in CLL. For a background on RT, please read this article by Dr. Weistner from the National Institutes of Health (NIH). Briefly, RT occurs when the usually slow growing CLL/SLL transforms into a more aggressive lymphoma, usually

March 28, 2018

ASH 2017: Dr. Mato on PET Scans Identifying Richter’s Transformation in CLL (chronic lymphocytic leukemia)

By Brian Koffman, MD and Anthony Mato, MD As we are getting better at controlling CLL and living longer, there is increasing concern about serious late complications including Richter’s Transformation (RT) or Richter’s Syndrome (RS) where the CLL “transforms” into a new more aggressive type of lymphoma. Here is

Richter’s Transformation

EHA 2021: Dr. Anthony Mato on pirtobrutinib (LOXO-305) for Richter’s transformation in chronic lymphocytic leukemia (CLL)

ASH 2020: Dr. Arnon Nagler on Safety and Efficacy of CD19-CAR T Cells in Richter’s Transformation After Targeted Therapy for Chronic Lymphocytic Leukemia (CLL)

ASCO 2020 Top 12” #3: A multicenter phase II study of venetoclax plus dose-adjusted R-EPOCH (VR-EPOCH) for Richter’s syndrome

ASH 2019: Dr. Mato Discusses a Novel Triple Therapy Clinical Trial for CLL/SLL, Richter’s Transformation and other Lymphomas

ASCO 2019: CLL Society Dr. Koffman’s Pick #7 “Stem Cell Transplant in Richter Transformation inn Chronic Lymphocytic Leukemia (CLL)”

EHA 2019: Dr. Matthew Davids On Richter’s Transformation in CLL (chronic lymphocytic leukemia)

ASH 2018: Dr. Wang on Richter’s Transformation in CLL (chronic lymphocytic leukemia)

ASH 2017: Dr. Mato on PET Scans Identifying Richter’s Transformation in CLL (chronic lymphocytic leukemia)

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