“There are three kinds of lies: lies, damned lies, and statistics.” I am certain many readers will be tempted to shy away from reading about how the mathematics of lab testing works, but if you stick with it, Dr. Susan Leclair’s two articles that follow will give you the
The methodologies for testing MRD are evolving and finding less than 1 in 10,000 cells by flow cytometry is today’s standard definition for undetectable minimal or measurable residual disease (uMRD). There is good reason to believe that the deeper levels achievable with next generation gene sequencing (NGS), capable of
The CLL Society worked with a broad coalition of other stakeholders in the MRD TESTING COLLABORATIVE to produce a glossary of terms for those new to MRD (minimal or measurable residual disease). The COLLABORATIVE offers several patient friendly MRD related resources.
Bone Marrow Results: What does less that one in a million mean? Dr. Brian Koffman explains both FLOW cytometry testing, which can find as few as one in 10,000 cancer cells, and CLONOSEQ testing, which can find one cancer cell in one million.