Clinical trials are critical for the development of new methods to prevent, detect, and treat cancer. Within clinical trials, researchers determine whether new treatments are safe and effective and work better than current treatments. Participating in a clinical trial may also offer the opportunity to gain access to newer or more treatment options and possibly save some of the cost of medications however there could be some undiscovered risks and downsides. Clinical trial inclusion and exclusion criteria determine whether you would be eligible for a specific trial. Most people first hear about clinical trials from their doctors, but you can search for clinical trials online on your own to explore what might be a good option. Discussing a potential trial would be part of the shared decision-making process you have with your CLL team.