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CLL Society Education On-Demand: The Evolving Role of BTKi’s in CLL

In science and medicine, information is constantly changing and may become out-of-date as new data emerge. All articles and interviews are informational only, should never be considered medical advice, and should never be acted on without review with your health care team.

Recorded June 28, 2022

The targeted therapy Bruton tyrosine kinase inhibitors (BTKi’s) have come a long way since revolutionizing CLL treatment with the arrival of ibrutinib. There are now other BTKi options such as acalabrutinib, zanubrutinib, and the next generation non-covalent BTK Inhibitor, pirtobrutinib. Join CLL Society and Dr. Matthew Davids from Dana Farber Cancer Institute to take a deep dive into different BTKi’s, how they work, how they compare to each other and other treatment options, potential side effects, and the future role of these therapies.


Robyn Brumble
Director of Scientific Affairs
CLL Society



Brian Koffman, MDCM (retired), MS Ed
Co-Founder, Executive Vice President, and Chief Medical Officer
CLL Society 


Matthew Davids - CLL Society

Matthew S. Davids, MD, MMSc
Associate Director, Center for Chronic Lymphocytic Leukemia
Dana Farber Cancer Institute

This program was made possible by grant support from AstraZeneca, BeiGene, Pharmacyclics, and Janssen.